PT-141

PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide and an active metabolite of Melanotan II. In preclinical research it is studied primarily for its agonist activity at the melanocortin-4 receptor (MC4R) in the central nervous system, alongside lower activity at other melanocortin receptors. This central MC4R focus distinguishes it from Melanotan II, which is studied largely for melanocortin-1 (pigmentation) pathways. Supplied at ≥99% HPLC purity for in-vitro research use only.

PT-141 is a metabolite of Melanotan II but has a distinct research profile. Melanotan II is a non-selective melanocortin agonist studied heavily for MC1R-mediated pigmentation pathways. PT-141 lacks the C-terminal amide of Melanotan II and is studied primarily for central MC4R signalling rather than pigmentation. They are related but distinct research tools targeting different primary pathways and are not interchangeable in a protocol. Not for human consumption — for research use only.

Reconstitution: Add 1–2mL of bacteriostatic water slowly down the inside wall of the vial with a 31G syringe and swirl gently until dissolved; do not shake. A 10mg vial reconstituted with 1mL BAC water yields a 10mg/mL solution. Storage: Lyophilised — store at −20°C for up to 24 months. Reconstituted — refrigerate at 2–8°C and use within 4 weeks, protected from light. BAC water is available at /products/bac-water-10ml. Not for human consumption — for research use only.

Legal status: PT-141 is legal to purchase in Australia for legitimate laboratory research purposes. It is not for human consumption, therapeutic, cosmetic, or veterinary use and is not TGA-approved in this form. Purchasers must be 18+ and confirm research-only intent. Quality: each batch is independently verified by third-party HPLC at ≥99% purity with a full COA including HPLC purity %, mass spectrometry identity confirmation, and sterility screening. Full COAs are available in our COA Library.

Peptide Warehouse Australia stocks PT-141 10mg and ships nationwide via Australia Post with full tracking. Orders placed before 12PM AEST dispatch the same business day from our Melbourne warehouse; orders after 12PM AEST dispatch the next business day. Standard Post $8.99 (2–6 business days); Express Post $13.99 (1–3 business days); free shipping on all orders over $199 AUD. All orders ship in discreet plain packaging with no external branding. Not for human consumption — for research use only.

PT-141 (Bremelanotide) is studied primarily for agonist activity at the central melanocortin-4 receptor (MC4R), engaging hypothalamic melanocortin signalling. This central mechanism distinguishes it from peripheral pigmentation-focused melanocortin compounds. Not for human consumption — for research use only.

PT-141 is the active metabolite that results from cleavage of Melanotan II, lacking the C-terminal amide of the parent. As a result it is studied largely for central MC4R signalling rather than the MC1R pigmentation pathways associated with Melanotan II (/products/melanotan-ii). Not for human consumption — for research use only.

Preclinical research has examined PT-141 in melanocortin-mediated arousal and motivation pathway models in animals, tied to central MC4R signalling. These are research-model findings and not evidence of any human effect. Not for human consumption — for research use only.