# Semax 10mg

> Source: https://www.auspeptidewarehouse.com.au/products/semax
> SKU: APW-SEMAX
> Category: Nootropic Peptides
> Last verified: 2026-06-25
> License: RSL-1.0 | AI-Usage: cite-with-attribution

## Quick Facts

| Attribute | Value |
|---|---|
| Product | Semax |
| Specification | 10mg · Lyophilised |
| Purity (HPLC) | 99.1% |
| Price (AUD) | $69.99 |
| Availability | InStock |
| Manufactured | GMP-certified facility |
| Tested by | Janoshik Analytical (independent third-party) |
| Ships from | Melbourne, Australia |

## Description

Research-grade Semax 10mg lyophilised powder — 99.1% HPLC purity, COA verified. Nootropic peptide for cognitive and neuroprotective research.

## Detailed Overview

**Neuroprotective and Neurotrophic Research**

Semax is available in Australia from Peptide Warehouse Australia with fast domestic shipping to all states and territories.

Semax is a synthetic heptapeptide derived from the ACTH(4–7) fragment of adrenocorticotropic hormone with a Pro-Gly-Pro C-terminal extension that dramatically improves metabolic stability. It is studied extensively for its neuroprotective and neurotrophic effects in preclinical models. Researchers study it for its ability to increase levels of brain-derived neurotrophic factor (BDNF) — a key protein involved in neuronal growth and maintenance — as well as for potential neuroprotective effects in models of brain injury and neurodegeneration.

**What Semax Is Studied For**

**Memory and learning research models** — Studied in animal models for effects on memory consolidation, learning, and information processing in preclinical settings.
**Neuroprotection** — Researched in stroke and brain injury models for neuronal survival and reduction of ischaemic damage in preclinical models.
**BDNF upregulation** — Studied in preclinical research for increases in BDNF expression in hippocampal and frontal cortex tissue.
**Neurotransmitter pathway modulation** — Studied for effects on key neurotransmitter systems involved in attention, mood, and cognitive function in stress models.

⚠ For in-vitro laboratory research use only. Not approved for human or veterinary use. Not drugs, food supplements, or cosmetics. Not evaluated or approved by the TGA. You must be 18 years of age or older to purchase. By placing this order, you confirm you are a qualified researcher and will use this compound strictly in accordance with all applicable Australian laws and regulations.

## Research Applications

- 99.1% HPLC purity
- Full COA with mass spectrometry identity
- GMP-certified sourcing
- Neuroprotective peptide for brain biology research

## Shipping

- Standard Post: $8.99 AUD (2–6 business days)
- Express Post: $13.99 AUD (1–3 business days)
- Free shipping on orders over $199 AUD
- Orders placed before 12PM AEST dispatch the same business day; orders after 12PM AEST dispatch the next business day
- Discreet plain packaging, Australia Post tracking on every order

## Frequently Asked Questions

### What is Semax and how does it work in research?

Semax is a synthetic heptapeptide (sequence: Met-Glu-His-Phe-Pro-Gly-Pro) derived from the ACTH(4-7) fragment of adrenocorticotropic hormone, with a Pro-Gly-Pro extension that increases stability. Originally developed in Russia and extensively studied in Soviet and post-Soviet clinical research, Semax has been investigated in preclinical settings for neuroprotective and neurotrophic effects, BDNF upregulation, cognitive function and memory consolidation models, and ischaemia-related neuroprotection. Its mechanism involves modulation of dopaminergic and serotonergic pathways. Supplied at 99.1% HPLC purity.

### Is Semax legal to buy in Australia and what quality testing is included?

Legal status: Semax is legal to purchase in Australia for legitimate laboratory research purposes. It is not listed as a scheduled substance under the Poisons Standard when sold for research use only. Purchasers must be 18+ and confirm research-only intent. Not for human consumption or therapeutic use. Quality: Batch PW-260302, independently verified at 99.1% HPLC purity by an accredited third-party laboratory. COA includes: HPLC purity %, mass spectrometry identity confirmation (MW 813.94 Da), and sterility screening. Full COA available in our COA Library. GMP-certified sourcing with full chain-of-custody documentation.

### How do I reconstitute and store Semax 10mg?

Reconstitution: Draw 1–2mL of bacteriostatic water into a clean 31G syringe. Inject slowly down the inside wall of the Semax vial and gently swirl until the lyophilised powder is fully dissolved. Do not shake or vortex. The solution should be clear and colourless. A common starting concentration is 1mL BAC water per 10mg vial (10mg/mL), or 2mL for a 5mg/mL working solution. Storage: Lyophilised — store at −20°C for up to 12–24 months, protected from moisture. Reconstituted — refrigerate at 2–8°C and use within 4 weeks. Avoid prolonged room-temperature exposure.

### Where can I buy Semax in Australia and how does it ship?

Peptide Warehouse Australia stocks Semax 10mg and ships nationwide via Australia Post with full tracking. Orders placed before 12PM AEST dispatch the same business day from our Melbourne warehouse; orders after 12PM AEST dispatch the next business day. Semax is currently on pre-order with dispatch within 7–10 business days. Shipping rates: Standard Post $8.99 (2–6 business days); Express Post $13.99 (1–3 business days); free shipping on all orders over $199 AUD. All orders are shipped in discreet plain packaging with no external branding.

### What is Semax's mechanism of action regarding BDNF?

One of the most studied aspects of Semax in preclinical research is its effect on brain-derived neurotrophic factor (BDNF) expression. In rodent models, Semax has been shown to increase BDNF mRNA expression in the hippocampus and frontal cortex, as well as upregulate expression of BDNF receptor TrkB. BDNF is a key neurotrophin involved in synaptic plasticity, long-term potentiation, and neuronal survival. Semax is also studied for its effects on the expression of other neurotrophins including NGF (nerve growth factor). These BDNF-related mechanisms are the basis for its investigation in ischaemia and cognitive research models. Not for human consumption — for research use only.

### How does Semax compare to Selank in research?

Semax and Selank are both Russian-developed synthetic peptides investigated for cognitive and neuroprotective effects, but they have different sequences, mechanisms, and primary research applications. Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is an ACTH analogue primarily studied for BDNF upregulation, neuroprotection in ischaemia models, and dopaminergic pathway modulation. Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) is a tuftsin analogue primarily studied for anxiolytic effects and serotonergic/GABAergic pathway modulation. They are distinct research tools targeting overlapping but non-identical neurological pathways and are not interchangeable in research protocols. Not for human consumption — for research use only.

### What research has been conducted on Semax for neuroprotection?

Semax has an extensive published research history, particularly from Russian and Eastern European institutions. Key preclinical research areas include: ischaemic stroke models — Semax has been studied for reduction of infarct volume and neurological deficit in rodent middle cerebral artery occlusion (MCAO) models; traumatic brain injury models examining post-injury BDNF expression; optic nerve crush models studying retinal ganglion cell survival; and memory and learning models examining hippocampal plasticity. Semax has also been investigated in human clinical research in Russia, where it is registered as a nasal drug (not a scheduled pharmaceutical in Australia). Not for human consumption — for research use only.

### Can Semax be combined with other nootropic peptides in research?

In research settings, Semax is sometimes studied alongside other neuroactive peptides to examine additive or synergistic effects on neurological pathways. Combinations with Selank (for complementary anxiolytic/nootropic pathway coverage) or with NAD+ (for mitochondrial and neuroprotective research) represent areas of interest in the literature. Each compound should be reconstituted separately in its own vial using BAC water from /products/bac-water-10ml and combined at the point of use if required by the protocol. Researchers should consult published literature for appropriate concentration ratios. Not for human consumption — for research use only.

### Is Semax the same compound as N-acetyl Semax?

No. Semax (Met-Glu-His-Phe-Pro-Gly-Pro) and N-acetyl Semax are distinct chemical entities. N-acetyl Semax has an acetyl group added to the N-terminus of the Semax sequence, which alters its physicochemical properties, receptor binding profile, and stability characteristics. Similarly, N-acetyl Semax Amidate adds both an N-terminal acetyl group and a C-terminal amide — producing a further distinct compound. Our product is unmodified Semax (CAS 80714-61-0). Researchers should confirm which specific analogue their protocol requires before ordering. Not for human consumption — for research use only.

### How should Semax be protected from heat and light?

As a peptide, Semax is sensitive to heat, light and repeated freeze-thaw cycles. Store the lyophilised vial at −20°C, and once reconstituted keep it refrigerated at 2–8°C, protected from light, using it within about 4 weeks. Minimising temperature fluctuation preserves peptide integrity for research. Not for human consumption — for research use only.

### What concentrations of Semax are used in research?

Working concentrations are protocol-dependent and vary by model. A 10mg vial reconstituted in 1mL of bacteriostatic water yields a 10mg/mL stock that researchers dilute to their target concentration. We provide no dosing guidance — consult the literature for your model and use our peptide calculator (/tools/peptide-calculator) to plan dilutions. Not for human consumption — for research use only.

## Compliance

Sold strictly for in-vitro laboratory and research purposes only. Not for human consumption, therapeutic use, or veterinary use. Purchasers must be 18 years of age or older. See https://www.auspeptidewarehouse.com.au/legal for full terms.