# L-Carnitine 500mg > Source: https://www.auspeptidewarehouse.com.au/products/l-carnitine > SKU: APW-LCAR > Category: Metabolic Research > Last verified: 2026-06-25 > License: RSL-1.0 | AI-Usage: cite-with-attribution ## Quick Facts | Attribute | Value | |---|---| | Product | L-Carnitine | | Specification | 500mg · Lyophilised | | Purity (HPLC) | >99% | | Price (AUD) | $89.99 | | Availability | InStock | | Manufactured | GMP-certified facility | | Tested by | Janoshik Analytical (independent third-party) | | Ships from | Melbourne, Australia | ## Description Research-grade L-Carnitine 500mg lyophilised powder — 99.0% HPLC purity, COA verified. Essential mitochondrial fatty acid transport cofactor — studied in beta-oxidation, CPT1 enzyme assays, acylcarnitine profiling, and energy metabolism research. ## Detailed Overview **Mitochondrial Fatty Acid Transport and Metabolic Research** L-Carnitine is available in Australia from Peptide Warehouse Australia with fast domestic shipping to all states and territories. L-Carnitine is a naturally occurring molecule synthesised endogenously from lysine and methionine, and it plays a critical role in how cells transport and oxidise fatty acids for energy. Without carnitine, long-chain fatty acids cannot enter the mitochondria for β-oxidation (Longo et al., Biochim Biophys Acta 2016). This makes L-Carnitine a rate-limiting factor in lipid metabolism, which is why it is used extensively in metabolic research. Researchers study it to understand cellular fatty acid utilisation, the effects of carnitine deficiency, and its relevance to metabolic disease models and carnitine deficiency disorders. The 500mg format supports extended cell culture protocols and enzyme assay work. **What L-Carnitine Is Studied For** **Mitochondrial fatty acid transport** — The primary research application: acts as the key transporter that moves fatty acids into mitochondria where they undergo oxidative metabolism. **Carnitine deficiency research** — Used to create and reverse carnitine-deficient states in cell and animal models, studying the downstream effects on energy metabolism. **Muscle metabolism** — Studied in skeletal muscle and heart tissue for how cells switch between fat and carbohydrate fuel sources during different energy demands. **Exercise physiology** — Investigated in preclinical models examining fatty acid oxidation during prolonged and high-intensity activity conditions. ⚠ For in-vitro laboratory research use only. Not approved for human or veterinary use. Not drugs, food supplements, or cosmetics. Not evaluated or approved by the TGA. You must be 18 years of age or older to purchase. By placing this order, you confirm you are a qualified researcher and will use this compound strictly in accordance with all applicable Australian laws and regulations. ## Research Applications - Rate-limiting cofactor for mitochondrial fatty acid beta-oxidation - 500mg format for cell culture, CPT1 enzyme kinetics, and metabolic flux assays - >99% HPLC purity (manufacturing specification) - Manufactured to a >99% HPLC purity specification - GMP-certified sourcing - Endogenous compound — extensively characterised across metabolic research literature ## Shipping - Standard Post: $8.99 AUD (2–6 business days) - Express Post: $13.99 AUD (1–3 business days) - Free shipping on orders over $199 AUD - Orders placed before 12PM AEST dispatch the same business day; orders after 12PM AEST dispatch the next business day - Discreet plain packaging, Australia Post tracking on every order ## Frequently Asked Questions ### What is L-Carnitine and what is its role in metabolism? L-Carnitine (CAS 541-15-1, MW 161.20 Da, C₇H₁₅NO₃) is an endogenous quaternary ammonium compound biosynthesised from lysine and methionine in the liver and kidneys. Its primary metabolic function is to shuttle long-chain acyl-CoA esters from the cytoplasm across the inner mitochondrial membrane via the carnitine-acylcarnitine translocase (CACT) system — a step that is rate-limiting for beta-oxidation of long-chain fatty acids. Without L-Carnitine, long-chain fatty acids cannot reach the mitochondrial matrix for oxidation. In research, L-Carnitine is used as the primary substrate in CPT1 enzyme assays, fatty acid oxidation models, and metabolic flux experiments. For research use only. ### What is the difference between L-Carnitine, Acetyl-L-Carnitine (ALCAR), and L-Carnitine-L-Tartrate? L-Carnitine is the base form responsible for mitochondrial fatty acid transport — the standard research substrate for CPT1 assays and beta-oxidation studies. Acetyl-L-Carnitine (ALCAR) is an acetylated form that crosses the blood-brain barrier more readily; it is additionally studied for its role in acetyl group donation to acetylcholine synthesis in neuronal models. L-Carnitine-L-Tartrate is a salt form with improved aqueous solubility commonly used in sports science research. Our product is L-Carnitine (the free zwitterionic inner salt form) — the appropriate choice for mitochondrial fatty acid transport, CPT1 enzyme kinetics, and acylcarnitine profiling research. Not for human consumption — for research use only. ### What in-vitro research models commonly use L-Carnitine? L-Carnitine is used across many cell-based and biochemical models: skeletal myocyte and cardiomyocyte fatty acid oxidation assays; CPT1 and CPT2 enzyme activity assays; acylcarnitine profiling via LC-MS/MS — a standard assay for fatty acid oxidation disorders; mitochondrial membrane potential studies using fluorescent probes; Seahorse XF metabolic flux analyser experiments (as supplementary substrate); carnitine deficiency rescue experiments in carnitine-depleted cell lines; and hepatocyte lipid accumulation models (NAFLD research). Not for human consumption — for research use only. ### How do I reconstitute and store L-Carnitine 500mg? Reconstitution: L-Carnitine is highly water-soluble. Draw the required volume of bacteriostatic water or sterile buffer and inject into the vial; swirl gently until dissolved. For 500mg vial: 5mL = 100mg/mL; 10mL = 50mg/mL; 50mL = 10mg/mL. L-Carnitine solution is relatively stable — refrigerate at 2–8°C and use within 4 weeks. Unlike glutathione, L-Carnitine has no significant oxidation concerns at normal handling temperatures. Store lyophilised powder at −20°C. ### Is L-Carnitine legal to buy in Australia for research? L-Carnitine is legal to purchase in Australia for legitimate laboratory research purposes. As an endogenous compound naturally present in meat and biosynthesised by the human body, it is not a scheduled substance when sold for research use. Purchasers must confirm research-only use. Our L-Carnitine 500mg is supplied as a research compound with >99% HPLC purity. Peptide Warehouse Australia dispatches nationwide from our Melbourne warehouse via Australia Post. Not for human consumption in this lyophilised research form. ### What is the CPT1/CPT2 shuttle system and how does L-Carnitine enable it? The carnitine shuttle moves long-chain fatty acids (>C12) across the inner mitochondrial membrane in three steps: CPT1 (outer membrane) converts long-chain acyl-CoA + L-Carnitine → acylcarnitine + CoASH; CACT (translocase) moves acylcarnitine into the mitochondrial matrix while transporting free carnitine out; CPT2 (inner membrane) converts acylcarnitine + CoASH → acyl-CoA + L-Carnitine, releasing the fatty acid for beta-oxidation. This shuttle is rate-limited by available L-Carnitine and CPT1 activity. CPT1 inhibitors (e.g. malonyl-CoA) and L-Carnitine supplementation are standard tools for studying mitochondrial fatty acid flux. Not for human consumption — for research use only. ## Compliance Sold strictly for in-vitro laboratory and research purposes only. Not for human consumption, therapeutic use, or veterinary use. Purchasers must be 18 years of age or older. See https://www.auspeptidewarehouse.com.au/legal for full terms.